Structure of LPP

LPP (lipopolyplex) nano-delivery platform is a core-shell structure with polymer-mixed mRNA as the core and lipids as the shell. Compared with traditional LNP platforms, the core-shell structured LPP particle is better at protecting mRNA, and is able to release mRNA gradually as the polymers are degraded.

With its exceptional selectivity to dendritic cells, the LPP platform can better activate immune response through antigen presentation to T cells, and therefore better achieve the therapeutic effect.